Dept. Llenguatges i Sistemes Informàtics
Universitat Politècnica de Catalunya
Campus Nord, Mòdul Omega, S106
c/ Jordi Girona Salgado, 1-3
08034 Barcelona
Spain
E-mail: bgel@lsi.upc.edu
Phone: 34 93 413 78 59
I am a PhD student at the Departament de Llenguatges i Sistemes Informàtics (Software Department) (LSI) of the Universitat Politècnica de Catalunya (UPC) under the supervision of Xavier Messeguer. I am part of the Algorithmics and Genetics (Alggen) group of ALBCOM Research Group.
I am also working with the Molecular Oncology Laboratory of the Human Anatomy and Embriology department of the Barcelona University (UB).
Research Interests
My research area is Computational Biology and Bioinformatics. I am interested in the developement of novel forms of interaction with genomic data and specially web based applications for the analysis and exploration of vast amounts of distributed data available throught the DAS system.
I am also working with microRNAs developing algorithms and applications for the discovery and prediction of microRNAs and its targets as well as studying their epigenetic regulation. I am also studying the relationship between SNPs and microRNAs and its expression levels and signatures in different cancer types. Viral microRNAs and their influence in host cells is also part of my work.
Papers
Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantation. Blood. 2008 Sep 4.
Overlapping expression of microRNAs in human embryonic colon and colorectal cancer. Cell Res. 2008 Aug;18(8):823-33.
Single nucleotide polymorphisms in nucleotide excision repair genes XPA, XPD, XPG and ERCC1 in advanced colorectal cancer patients treated with first-line oxaliplatin/fluoropyrimidine. Oncology. 2007;72(5-6):364-70. Epub 2008 Jan 17.
MicroRNA expression profiling in classic Hodgkin lymphoma. Blood. 2008 Mar 1;111(5):2825-32. Epub 2007 Dec 18.
Two Doses of oxaliplatin with capecitabine (XELOX) in metastatic colorectal cancer. Clin Colorectal Cancer. 2007 Sep;6(9):634-40
Single-nucleotide polymorphisms in base excision repair, nucleotide excision repair, and double strand break genes as markers for response to radiotherapy in patients with Stage I to II head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2006 Nov 15;66(4):1022-30. Epub 2006 Sep 18.